Use:
1. Collect some autologous bone, if possible (blur, scraper) and put it in a
sterile container
2. Open the bottle
3. Drop the bottle content into the sterile container
4. Hydrate with sterile physiological solution for 1‐2 minutes
5. Graft the mixture
6. Protect the grafted site with a proper membrane
General hints and precautions:
Grafting the granules: Place the granules in the grafting site in order to make them stable and still.
Avoid excessive compression. Too much compression can make the space
between adjacent granules decrease to such a point that angiogenesis is
hindered.
They are indicated for medium‐size reconstruction, in 4‐3 walls cavities. The
cancellous components remodels in 4‐6 months, the cortical one in 8‐12
months (the remodeling time is approximate since, as a cell‐mediated
remodeling process occurs, the total substitution time depends on the
beginning anatomical condition: the ratio between the receiving vital bone
surface and the grafted volume). The cortical component needs more time to
be remodeled given its greater density. Remodeling, anyway, is total (the
bone substitute will be replaced with new formed bone).
Indications:
1. Intact post‐extractive sockets, in order to preserve the vestibular wall,anticipating an implant placement
Hydrate the granules as described in the “Use” paragraph. Place them in the
post‐extractive socket after cleaning and preparing it. Detach slightly the flap
around the socket and place a pericardium Heart, after shaping it. The edges of
the membrane must be inserted below the edges ofthe flap. Suture with a cross
stitch.
2. Sinus lift (traditional Misch approach, or Misch approach and Tulasne
variation)
Prepare the cavity according to the technique described by Misch. Prepare the
granular mixture as described in the “Use” paragraph, and proceed to graft
the mixture as already described. Even if there’s no total agreement in
literature about the use of a collagen membrane, we advise for the covering of
the access window with a collagen membrane.
3. Filling the ridge after a “split crest”
Perform the crest splitting according to the preferred surgical approach; place
the implants or use bone distracters to increase the gap width. Prepare the
granular mixture as described in the “Use” paragraph, and proceed to graft
the mixture as already described. Protect the graft with a Heart,pericardium
membrane is preferred.
4. As a filler for the remaining gaps between adjacent blocks after an onlay graft
Prepare the granular mixture as described in the “Use” paragraph, and
proceed to graft the mixture as already described (protect the graft with a
Heart Pericardium membrane.
They can be used also for:
‐ Periodontal defects (every type of)
‐ Peri‐implant defects
‐ Sinus lift, crestal approach according to Summers
Made in Italy
See Product Catalog
BIO-GEN MIX
Granular bone substitutes are the most used, traditional format. Biogen granular grafts are available in different formats.
- MORE DETAILS
- Granular grafts are available as cancellous granules, cortical granules or a mixture of both.
- Spongy granules remodels in 4-6 months, cortical granules in 8-12 months.
- Cancellous granules should be grafted in small, 4-walls cavities.
- If the volume is greater and bone walls are missing, cortical granules are preferred.
- The mixture has both components and can be used for all the applications
Indications:
- Periodontal defects
- Peri-implant defects
- Post extractive sockets
- Sinus lift
Made in Italy
